(Ala¹³)-Apelin-13 (human, bovine, mouse, rat)

Description:

Apelin -13 is a vasoactive peptide and one of the most effective endogenous inotropic agents known. This peptide, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor

Sequence:

QRPRLSHKGPMPA

General

References

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Name	(Ala¹³)-Apelin-13 (human, bovine, mouse, rat)
Category	Apelin Peptides
One Letter Code	QRPRLSHKGPMPA
Three Letter Code	{Gln}{Arg}{Pro}{Arg}{Leu}{Ser}{His}{Lys}{Gly}{Pro}{Met}{Pro}{Ala}
Molecular Weight	1474.700
Application	Cardiovascular System & Diseases

Macaluso, NJ Maximilian, et al. "Discovery of a competitive apelin receptor (APJ) antagonist." ChemMedChem 6.6 (2011): 1017-1023.

Lee, Dennis K., et al. "Modification of the terminal residue of apelin-13 antagonizes its hypotensive action." Endocrinology 146.1 (2005): 231-236.