TRAP-6

Description:

The hexapeptide acts as a thrombin receptor activator. It is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca²⁺.

Sequence:

SFLLRN
  • General
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  • Name TRAP-6
    Category PAR (Protease Activated Receptor) Peptides and Related Peptide
    One Letter Code SFLLRN
    Three Letter Code {Ser}{Phe}{Leu}{Leu}{Arg}{Asn}
    Molecular Weight 748.880
    Application Cardiovascular System & Diseases, Hematology,Thrombin Related Peptides
    I.E.Allijn et al.,PLoS One,11,e0155325(2016)
    F.Bonhomme et al.,Platelets,26,324(2015)
    K.H.Driesbaugh et al.,J. Biol. Chem.,290,3529(2015)
    M.T.Aatonen et al.,J. Extracell. Vesicles,3,(2014)
    J.W.Jin et al.,Clin. Appl. Thromb. Hemost.,20,278(2014)
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