Apelin - 36 (human)

Description:

This apelin-36 peptide inhibits infection of APJ-expressing cells caused by some HIV-1 and HIV-2

Sequence:

LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF
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  • Name Apelin - 36 (human)
    Category Apelin Peptides
    One Letter Code LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF
    Three Letter Code {Leu}{Val}{Gln}{Pro}{Arg}{Gly}{Ser}{Arg}{Asn}{Gly}{Pro}{Gly}{Pro}{Trp}{Gln}{Gly}{Gly}{Arg}{Arg}{Lys}{Phe}{Arg}{Arg}{Gln}{Arg}{Pro}{Arg}{Leu}{Ser}{His}{Lys}{Gly}{Pro}{Met}{Pro}{Phe}
    Molecular Weight 4195.900
    Application Infectious Disease, Virology, Cardiovascular System & Diseases
    Cayabyab, Mark, et al. "Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry." Journal of virology 74.24 (2000): 11972-11976.
    Goazigo, Annabelle Reaux-Le, et al. "Dehydration-induced cross-regulation of apelin and vasopressin immunoreactivity levels in magnocellular hypothalamic neurons." Endocrinology 145.9 (2004): 4392-4400.
    Picault, François-Xavier, et al. "Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas." European Journal of Cancer 50.3 (2014): 663-674.
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