(Pyr¹)-Apelin-13 (human, bovine, mouse, rat)

Description:

(Pyr¹)-Apelin-13 is maybe the final product of the post-translational modification of apelin. It could be required for the maintenance of insulin sensitivity.

Sequence:

{pGLU}RPRLSHKGPMPF

General

References

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Name	(Pyr¹)-Apelin-13 (human, bovine, mouse, rat)
Category	Apelin Peptides
One Letter Code	{pGLU}RPRLSHKGPMPF
Three Letter Code	{pGLU}{Arg}{Pro}{Arg}{Leu}{Ser}{His}{Lys}{Gly}{Pro}{Met}{Pro}{Phe}
Molecular Weight	1533.820
Application	Diabetes

Drougard, Anne, et al. "Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice." Scientific reports 6.1 (2016): 1-12.

Drougard, Anne, et al. "Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes." Antioxidants & redox signaling 20.4 (2014): 557-573.

Picault, François-Xavier, et al. "Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas." European Journal of Cancer 50.3 (2014): 663-674.

Pope, George R., et al. "Central and peripheral apelin receptor distribution in the mouse: species differences with rat." Peptides 33.1 (2012): 139-148.

Duparc, Thibaut, et al. "Central apelin controls glucose homeostasis via a nitric oxide-dependent pathway in mice." Antioxidants & redox signaling 15.6 (2011): 1477-1496.