(Tyr⁵·¹²,Lys⁷)-Polyphemusin II

Description:

Anti-HIV synthetic peptide. It shows strong anti-human immunodeficiency virus activity in HIV-infected MT-4 cells

Sequence:

RRWCYRKCYKGYCYRKCR-NH₂ (Disulfide bridge: 4-17, 8-1)

General

References

Comments (0)

Name	(Tyr⁵·¹²,Lys⁷)-Polyphemusin II
Category	Antiviral Peptides
One Letter Code	RRWCYRKCYKGYCYRKCR-NH₂ (Disulfide bridge: 4-17, 8-1)
Three Letter Code	{Arg}{Arg}{Trp}{Cys}{Tyr}{Arg}{Lys}{Cys}{Tyr}{Lys}{Gly}{Tyr}{Cys}{Tyr}{Arg}{Lys}{Cys}{Arg}-NH₂ (Disulfide bridge: 4-17, 8-1) (Disulfide bridge: 4-17, 8-1)
Molecular Weight	2487.010
Application	Infectious DiseaseVirology

Hatse, Sigrid, Jan Balzarini, and Sandra Liekens. "Stromal cell-derived factor 1 (CXCL12) binds to endothelial cells and signals through a receptor different from CXCR4." Biochemical and biophysical research communications 348.1 (2006): 192-199.

Tamamura, Hirokazu, et al. "Structure-activity relationships of an anti-HIV peptide, T22." Biochemical and biophysical research communications 205.3 (1994): 1729-1735.