Prokineticin 2 Isoform 2 (human)

Description:

Prokineticin 2 is one of the first neuropeptides that appears to directly convey circadian rhythm signaling to other CNS structures.The peptide has the capacity to strongly suppress nocturnal locomotor activity.

Sequence:

AVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK (Disulfide bridge: (Disulfide bonds, air oxidized)
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  • Name Prokineticin 2 Isoform 2 (human)
    Category Neuropeptide Y (NPY), Analogs and Fragments
    One Letter Code AVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLACLRTSFNRFICLAQK (Disulfide bridge: (Disulfide bonds, air oxidized)
    Three Letter Code {Ala}{Val}{Ile}{Thr}{Gly}{Ala}{Cys}{Asp}{Lys}{Asp}{Ser}{Gln}{Cys}{Gly}{Gly}{Gly}{Met}{Cys}{Cys}{Ala}{Val}{Ser}{Ile}{Trp}{Val}{Lys}{Ser}{Ile}{Arg}{Ile}{Cys}{Thr}{Pro}{Met}{Gly}{Lys}{Leu}{Gly}{Asp}{Ser}{Cys}{His}{Pro}{Leu}{Thr}{Arg}{Lys}{Val}{Pro}{Phe}{Phe}{Gly}{Arg}{Arg}{Met}{His}{His}{Thr}{Cys}{Pro}{Cys}{Leu}{Pro}{Gly}{Leu}{Ala}{Cys}{Leu}{Arg}{Thr}{Ser}{Phe}{Asn}{Arg}{Phe}{Ile}{Cys}{Leu}{Ala}{Gln}{Lys} (Disulfide bridge: (Disulfide bonds, air oxidized)
    Molecular Weight 8792.550
    Application
    J.V.Gardiner et al.,Diabetes,59,397 (2010)
    Q.Y.Zhou and M.Y.Cheng,FEBS J.,272,5703(2005)
    G.T.Cottrell et al.,J. Neurosci.,24,2375(2004)
    M.-Y.Cheng et al.,Nature,417,405(2002)
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