Dermcidin, DCD - 1L/Dermcidin-1L (human)

Description:

Dermcidin-1L (DCD-1L) has a net negative charge with a Leu residue on the C-terminus.

Sequence:

SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL

General

References

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Name	Dermcidin, DCD - 1L/Dermcidin-1L (human)
Category	Antimicrobial and Related Peptides
One Letter Code	SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
Three Letter Code	{Ser}{Ser}{Leu}{Leu}{Glu}{Lys}{Gly}{Leu}{Asp}{Gly}{Ala}{Lys}{Lys}{Ala}{Val}{Gly}{Gly}{Leu}{Gly}{Lys}{Leu}{Gly}{Lys}{Asp}{Ala}{Val}{Glu}{Asp}{Leu}{Glu}{Ser}{Val}{Gly}{Lys}{Gly}{Ala}{Val}{His}{Asp}{Val}{Lys}{Asp}{Val}{Leu}{Asp}{Ser}{Val}{Leu}
Molecular Weight	4818.500
Application	Antimicrobial & Antiviral PeptidesCosmetic Peptides & Dermatology

Niyonsaba, Francois, et al. "Multifunctional antimicrobial proteins and peptides: natural activators of immune systems." Current pharmaceutical design 15.21 (2009): 2393-2413.

Steffen, H., et al. "Naturally processed dermcidin-derived peptides do not permeabilize bacterial membranes and kill microorganisms irrespective of their charge." Antimicrobial agents and chemotherapy 50.8 (2006): 2608-2620.

Schittek, Birgit, et al. "Dermcidin: a novel human antibiotic peptide secreted by sweat glands." Nature immunology 2.12 (2001): 1133-1137.