C - Type Natriuretic Peptide (32 - 53) (human, porcine)

Description:

C-type Natriuretic Peptide (CNP) is the most highly conserved of natriuretic peptides between species. It is derived from a 126 amino acid preprohormone. It is a vasorelaxant and inhibitor of smooth muscle cell proliferation and may be involved in coagulation and fibrinogenesis by modulating endothelial cells.

Sequence:

GLSKGCFGLKLDRIGSMSGLGC (Disulfide bridge: 6-22)

General

References

Comments (0)

Name	C - Type Natriuretic Peptide (32 - 53) (human, porcine)
Category	Natriuretic Peptides
One Letter Code	GLSKGCFGLKLDRIGSMSGLGC (Disulfide bridge: 6-22)
Three Letter Code	{Gly}{Leu}{Ser}{Lys}{Gly}{Cys}{Phe}{Gly}{Leu}{Lys}{Leu}{Asp}{Arg}{Ile}{Gly}{Ser}{Met}{Ser}{Gly}{Leu}{Gly}{Cys} (Disulfide bridge: 6-22) (Disulfide bridge: 6-22)
Molecular Weight	2197.700
Application	Cardiovascular System & Diseases

Ref: Kalra, P. et al. Eur. Heart J. 22, 997 (2001);

Z.Q.Li et al.,Mol. Med. Rep.,11,159(2015)

A.Mietens et al.,PloS One,9,e92603 (2014)

J.A.Kennedy et al.,Eur. J. Pharmacol.,602,28(2009)