Ac-(D-Arg¹⁰,Cys¹¹,D-Phe¹⁴,Cys¹⁷)-β-MSH (10-17) amide

Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency.

Ac-{D-Arg}CEH{D-Phe}RWC-NH₂ (Disulfide bridge: 2-8)

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Name	Ac-(D-Arg¹⁰,Cys¹¹,D-Phe¹⁴,Cys¹⁷)-β-MSH (10-17) amide
Category	Melanocyte-Stimulating Hormone (MSH) and MSH-Sequence
One Letter Code	Ac-{D-Arg}CEH{D-Phe}RWC-NH₂ (Disulfide bridge: 2-8)
Three Letter Code	Acetylation-{D-Arg}{Cys}{Glu}{His}{D-Phe}{Arg}{Trp}{Cys}-NH₂ (Disulfide Bridge: 2-8) (Disulfide bridge: 2-8)
Molecular Weight	1175.360
Application	Obesity ResearchPituitary & Hypothalamic Hormones

S.Veiksina et al.,Biochim. Biophys. Acta,1838,372 (2014)

J.P.Mayer et al.,J. Med. Chem.,48,3095 (2005)