Kisspeptin-54 (human)

Description:

Kisspeptin-54, an endogenous ligand of the G protein-coupled receptor GPR54, is a key regulator of the hypothalamo-pituitary-gonadal (HPG) axis. It stimulates LH and FSH secretion.

Sequence:

GTSLSPPPESSGSRQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRF-NH₂

General

References

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Name	Kisspeptin-54 (human)
Category	Kisspeptin Peptides
One Letter Code	GTSLSPPPESSGSRQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRF-NH₂
Three Letter Code	{Gly}{Thr}{Ser}{Leu}{Ser}{Pro}{Pro}{Pro}{Glu}{Ser}{Ser}{Gly}{Ser}{Arg}{Gln}{Gln}{Pro}{Gly}{Leu}{Ser}{Ala}{Pro}{His}{Ser}{Arg}{Gln}{Ile}{Pro}{Ala}{Pro}{Gln}{Gly}{Ala}{Val}{Leu}{Val}{Gln}{Arg}{Glu}{Lys}{Asp}{Leu}{Pro}{Asn}{Tyr}{Asn}{Trp}{Asn}{Ser}{Phe}{Gly}{Leu}{Arg}{Phe}-NH₂
Molecular Weight	5857.510
Application	Cancer ResearchPituitary & Hypothalamic Hormones

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G.M.Nijher et al.,Br. J. Clin. Pharmacol.,70,674 (2010)

W.S.Dhillo et al.,J. Clin. Endocrinol. Metab.,92,3958(2007)

S.B.Seminara and U.B.Kaiser,Endocrinology,146,1686(2005)

W.S.Dhillo et al.,J. Clin. Endocrinol. Metab.,90,6609(2005)

M.L.Gottsch et al.,Endocrinology,145,4073 (2004)