[NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22 - 27)

Description:

This 22-27 fragament of Human Islet Amyloid Polypeptide (IAPP) has N-methylation of the amide bonds at position 24 and 26. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenes

Sequence:

NF-(NMe-G)-A-(NMe-I)-L
  • General
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  • Name [NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22 - 27)
    Category Islet Amyloid Polypeptides (IAPP)
    One Letter Code NF-(NMe-G)-A-(NMe-I)-L
    Three Letter Code {Asn}{Phe}{(nme-Gly)}{Ala}{(nme-Ile)}{Leu}
    Molecular Weight 661.800
    Application
    Yan, L. et al. PNAS 103, 2046 (2006),
    Kapurniotu, A., et al. J. Mol. Biol. 315, 339 (2002),
    Tatarek-Nossol, M. et al. Cell Press 12, 797 (2005).
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