Humanin, HN

Description:

Humanin (HN) is a polypeptide suppressing neuronal cell death induced by several familial Alzheimer's disease genes and by amyloid β-protein (1-43) (human).

Sequence:

MAPRGFSCLLLLTSEIDLPVKRRA
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  • Name Humanin, HN
    Category Humanins
    One Letter Code MAPRGFSCLLLLTSEIDLPVKRRA
    Three Letter Code {Met}{Ala}{Pro}{Arg}{Gly}{Phe}{Ser}{Cys}{Leu}{Leu}{Leu}{Leu}{Thr}{Ser}{Glu}{Ile}{Asp}{Leu}{Pro}{Val}{Lys}{Arg}{Arg}{Ala}
    Molecular Weight 2687.300
    Application Alzheimer's Disease, Mitochondrial Peptides
    Ref: Hashimoto, Y. et al. Proc. Natl. Acad. Sci. USA 98, 6336 (2001).
    P.G.Sreekumar et al.,Invest. Ophthalmol. Vis. Sci.,57,1238(2016)
    C.Lee et al.,Aging Cell,13,958 (2014)
    E.Moretti et al.,Fertil. Steril.,94,2888(2010)
    B.Zapala et al.,Pharmacol. Rep.,62,767 (2010)
    Y.Hashimoto et al.,Biochem. Biophys. Res. Commun.,283,460 (2001)
    Y.Hashimoto et al.,Proc. Natl. Acad. Sci. USA,98,6336 (2001)
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