Endotoxin Inhibitor

Description:

The cyclic peptide KTKCKFLKKC has a structural resemblance with the peptide antibiotic and endotoxin inhibitor polymyxin B,and can be used as an adjuvant for antibiotic therapy.

Sequence:

KTKCKFLKKC (Disulfide bridge: 4-10)

General

References

Comments (0)

Name	Endotoxin Inhibitor
Category	Antimicrobial and Related Peptides
One Letter Code	KTKCKFLKKC (Disulfide bridge: 4-10)
Three Letter Code	{Lys}{Thr}{Lys}{Cys}{Lys}{Phe}{Leu}{Lys}{Lys}{Cys} (Disulfide bridge: 4-10) (Disulfide bridge: 4-10)
Molecular Weight	1224.600
Application	Antimicrobial & Antiviral PeptidesImmunomodulating Agents

Maslanik, Thomas, et al. "Commensal bacteria and MAMPs are necessary for stress-induced increases in IL-1β and IL-18 but not IL-6, IL-10 or MCP-1." PloS one 7.12 (2012).

Katafuchi, Toshihiko, et al. "Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats." Molecular brain research 118.1-2 (2003): 24-32.

Kuhn, Roger, et al. "Effect of intraperitoneal application of an endotoxin inhibitor on survival time in a laparoscopic model of peritonitis in rats." World journal of surgery 29.6 (2005): 766-770.

Katafuchi, Toshihiko, et al. "Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats." Molecular brain research 118.1-2 (2003): 24-32.