ACTH (1 - 24) (human)

Description:

A C-terminally truncated ACTH, ACTH (1-24) has full biological activity of the (1-39) peptide, but it is less immunogenic than the full-length peptide hormone.

Sequence:

SYSMEHFRWGKPVGKKRRPVKVYP
  • General
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  • Name ACTH (1 - 24) (human)
    Category ACTH and Related Peptides
    One Letter Code SYSMEHFRWGKPVGKKRRPVKVYP
    Three Letter Code H}{Ser}{Tyr}{Ser}{Met}{Glu}{His}{Phe}{Arg}{Trp}{Gly}{Lys}{Pro}{Val}{Gly}{Lys}{Lys}{Arg}{Arg}{Pro}{Val}{Lys}{Val}{tyr}{pro}{OH
    Molecular Weight 2933.500
    Application
    Scheys, Joshua O., Joanne H. Heaton, and Gary D. Hammer. "Evidence of adrenal failure in aging Dax1-deficient mice." Endocrinology 152.9 (2011): 3430-3439.
    Santoro, Nicola, et al. "Prevalence of pathogenetic MC4R mutations in Italian children with early onset obesity, tall stature and familial history of obesity." BMC medical genetics 10.1 (2009): 25.
    Hentges, Shane T., et al. "Proopiomelanocortin expression in both GABA and glutamate neurons." Journal of Neuroscience 29.43 (2009): 13684-13690.
    Harmer, Stephen C., et al. "Evidence of a possible role for Lys-γ3-MSH in the regulation of adipocyte function." The Journal of endocrinology 196.1 (2008): 149.
    Davies, Evelyn, et al. "Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice." Endocrinology 148.3 (2007): 1030-1038.
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