Biotin - ACTH (1 - 39) (human)

Description:

Used for ELISA assays. ACTH also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R).

Sequence:

Biotin-SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF

General

References

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Name	Biotin - ACTH (1 - 39) (human)
Category	ACTH and Related Peptides
One Letter Code	Biotin-SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
Three Letter Code	Biotin-{Ser}{Tyr}{Ser}{Met}{Glu}{His}{Phe}{Arg}{Trp}{Gly}{Lys}{Pro}{Val}{Gly}{Lys}{Lys}{Arg}{Arg}{Pro}{Val}{Lys}{Val}{Tyr}{Pro}{Asn}{Gly}{Ala}{Glu}{Asp}{Glu}{Ser}{Ala}{Glu}{Ala}{Phe}{Pro}{Leu}{Glu}{Phe}
Molecular Weight	4767.600
Application	ELISA assays

Moreno-Guzmán, María, et al. "Ultrasensitive detection of adrenocorticotropin hormone (ACTH) using disposable phenylboronic-modified electrochemical immunosensors." Biosensors and Bioelectronics 35.1 (2012): 82-86.

Stewart, Paul M., and Zygmunt S. Krozowski. "11β-Hydroxysteroid dehydrogenase." Vitamins & Hormones. Vol. 57. Academic Press, 1997. 249-324.

Elias, L. L. K., and A. J. L. Clark. "The expression of the ACTH receptor." Brazilian Journal of Medical and Biological Research 33.10 (2000): 1245-1248.

Latronico, A. C. "Role of ACTH receptor in adrenocortical tumor formation." Brazilian Journal of Medical and Biological Research 33.10 (2000): 1249-1252.